Being faced with any of several types of dis-ease brings to light many things about our wonderfully made bodies. A couple major elements within us determine what and who we will be;
What I am about to tell everyone dealing with dis-ease is to pay attention to this;
Of course the story that led to this discovery
A couple nights ago I’m lying in bed next to my girlfriend and we are side-by-side talkin and makin google eyes at each other and talkin silly when Jennie asked “Why did you shave your chest?” I said “I didn’t” we started looking and come to see that the hairs that used to be in abundance on my chest are GONE! The hairs on my arms, GONE! Skin silky smooth, Muscle tone getting soft and losing it.
IS IT THE CANCER????????
Now the backstory that led to this
Natalie came with me to a oncology visit about 4 months ago. She told me to ask for an Estrogen Panel, citing that we have stripped most of the Testosterone out of me,
WHAT ABOUT THE LEVELS OF ESTROGEN?
My Estrogen Levels were 131pg/ml normal levels are 40 – 115pg/ml in males.
I’m high ~ .
Estrogen is considered to be the “female” hormone, whereas testosterone is considered the “male” hormone. However, both hormones are present in both sexes.
Estrogen and Disease
Estrogen influences many physiological processes including reproduction, cardiovascular health, bone integrity, cognition, and behavior. Given this extensive role for estrogen in human physiology, it is not surprising that estrogen is also implicated in the development or progression of numerous diseases.
Low Estradiol and Testosterone Predict Mortality in Aging Men
Sales of testosterone replacement drugs have surged more than 20-fold in response to studies linking low testosterone to a host of common maladies.
In a recent study of 3,014 men aged 69-80 years, serum levels of testosterone and estradiol were measured during a mean follow-up of 4.5 years. Men with low testosterone had 65% greater all-cause mortality, while men with low estradiol suffered 54% more deaths.25
Those men low in estradiol and testosterone were almost twice as likely to die (a 96% increase in mortality) compared to men in the optimal ranges.25
This large study of aged men corroborates prior published reports linking imbalances of testosterone and/or estradiol with greater incidences of degenerative disease and death.26-36
New Study Published in the Journal of the American Medical Association
Conventional doctors tend to ignore hard science until it appears in their own medical journals.
A study published in the Journal of the American Medical Association (JAMA) measured blood estradiol (a dominant estrogen) in 501 men with chronic heart failure. Compared to men in the balanced estrogen quintile, men in the lowest estradiol quintile were 317% more likely to die during a 3-year follow-up, while men in the highest estradiol quintile were 133% more likely to die.24
The men in the balanced quintile—with the fewest deaths—had serum estradiol levels between 21.80 and 30.11 pg/mL. This is virtually the ideal range that Life Extension® has long recommended male members strive for.
The men in the highest quintile who suffered 133% increased death rates had serum estradiol levels of 37.40 pg/mL or above. The lowest estradiol group that suffered a 317% increased death rate had serum estradiol levels under 12.90 pg/mL.
The dramatic increase in mortality in men with unbalanced estrogen (i.e., estradiol levels either too high or too low) is nothing short of astounding. It uncovers a gaping hole in conventional cardiology practice that is easily correctable.
This study revealing the lethal dangers of estrogen imbalance was published in conventional medicine’s Bastille of knowledge—the Journal of the American Medical Association. Physicians no longer have a basis to question male Life Extension® members who take aggressive approaches to maintain their serum estradiol levels in optimal ranges.
My oncologist sat there and asked us of “Why?” we would need such a test ~~`and “What would do with the results?:
So my body is tellin me I have too much estrogen by shedding my body hair, weakening muscle tone, emotional roller coaster
I gotta believe this is going on in everybody that has some hormone manipulation going on, male/female.
Yes, these studies did not point the finger towards cancer, but the implications of these reports surely applies to that ALL dis-ease.
“Estrogen and Prostate Cancer”
The role that estrogen plays in malignant prostate disease is contradictory and complex. Some studies indicate that estrogen and its toxic metabolites are a cause of prostate cancer.15,16 Yet once prostate cancer develops, certain estrogen compounds demonstrate anticancer effects.
This paradox can be explained by the mechanisms that estradiol (and its toxic metabolites) uses to damage prostate cell DNA,17 causing gene mutations that result in the loss of cell growth regulatory control, i.e. cancer. Interestingly, once a prostate tumor manifests, estrogen may exert anti-tumor effects, though cancer cells eventually become resistant to estrogen drugs and then even use endogenous estrogen to fuel their growth.
The fact that estrogen may temporarily exert anti-tumor effects in certain types of prostate cancer cells does not diminish the argument that estrogen may have contributed to the initiation of the same cancer. For example, in a study published two years ago, researchers discovered that when “estradiol is added to testosterone treatment of rats, prostate cancer incidence is markedly increased and even a short course of estrogen treatment results in a high incidence of prostate cancer.” These scientists hypothesize that metabolites of estrogens can be converted to reactive intermediates that can adduct to DNA and cause generation of reactive oxygen species; thus, estradiol is a weak DNA-damaging carcinogen that causes DNA damage to prostate cell genes.18 This kind of damage to DNA regulatory genes is what initiates prostate cancer.
Many published studies, however, show no association between high blood estradiol levels and diagnosed prostate cancers.19
One reason there are not more diagnosed prostate cancers in men with high estrogen may be that the high estradiol level that initiated DNA damage then serves to keep prostate cancer temporarily under control once it develops.
An interesting mechanism by which certain prostate cancer cells become resistant to estradiol therapy is the development of components in cancer cells that selectively remove estradiol from the tumor cells. If our normal cells were only as adaptive as cancer cells, we could possibly become biologically immortal.
Another reason why estradiol blood levels may not correlate with prostate cancer incidence is the ability of prostate cells to produce their own estradiol (by making their own aromatase enzyme).
Although evidence is conflicting, there is a clear indication that local synthesis of estrogen in the prostate gland itself may be significant in prostate tumor development.16
All of this helps validate the importance of nutrients Life Extension male members take to block the carcinogenic effects of estrogen within the prostate gland.
An analogy to how excess estrogen can first damage DNA regulatory genes to cause cancer and then act as a prostate cancer suppressor can be seen with chemotherapy drugs. The mechanism by which most chemo drugs kill cancer cells is to inflict massive damage to cellular DNA.
While chemo drugs kill cancer cells, they simultaneously damage healthy DNA and can increase the risk of future cancers. It appears that excess estrogen damages prostate cell DNA to initiate cancer, but then acts as a temporary prostate cancer suppressor. In presenting this analogy, I am not implying that estrogen in men is as dangerous as toxic chemo drugs. I am showing that something that suppresses cancer cell propagation (like estrogen) can also cause cancer”
Word to the wise ~~~ check that out!
There are too many men, already diagnosed with PC, who are not taking an active role in their own recovery. Many believe that because they are consulting a professional with a medical degree (who may also command a generous salary), all or part of this equates with getting the very best advice and treatment.
Wrong. In today’s world of rapid pace, where medicine is practiced with 15-minute office visits and where physicians are too busy to read and translate much of what is being published, the patient and his partner must not take a passive role and assume that all that can be done is being done.